Differin Gel Reviews (2024 UPDATE): Is It Safe And Effective?


What Is Differin Gel?

Differin Gel is an over-the-counter and FDA approved acne treatment gel.

The gel is retinoid adapalene based. This is unlike many other acne treatments on the market which are salicylic acid based.

The company prides themselves on being a unique and new approach to eliminating and preventing acne.

Differin Gel


Who Makes Differin Gel?

This product is made by Galderma Laboratories.

They were founded in 1961 and have headquarters in Fort Worth, Texas.

If you have any questions about this product, you can contact them by filling out a contact form on the website.

Best Differin Gel Alternative?

Due to all the negative reviews about Differin Gel, we’ve been looking for a competitive product that was proven more effective. We checked several of them with deception, and finally came around a real effective acne treatment. You can read its review HERE.

Who Is Differin Gel For?

This acne treatment gel is for anyone who is over the age of 12 and suffers from mild or moderate acne.

It is not recommended for use by those who are dealing with severe acne.

If you are on medication, pregnant, breastfeeding, or struggling with severe acne, you should contact a doctor before using this product.

How Does Differin Gel Work?

The main ingredient in this product is a retinoid called adapalene.

Adapalene works much differently compared to other acne treatments that contain salicylic acid or benzoyl peroxide.

It targets the source of the acne instead of just eliminating the visibility of it. Adapalene targets the pores to unclog them and keep them clean.

These retinoids contain vitamin A which makes the cells create a healthier environment for future skin growth.

It is also considered an anti-inflammatory, which can reduce redness and pimples.

Other ingredients work to restore the skin tone and texture after the acne is cleared. They also work to protect the skin from future breakouts of blackheads, whiteheads, and pimples.

Differin Gel Ingredients

As previously mentioned, this gel has one main active ingredient — a retinoid called adapalene.

The inactive ingredients are:

  • Carbomer 940
  • Edetate disodium
  • Methylparaben
  • Poloxamer 182
  • Propylene glycol
  • Purified water
  • Sodium hydroxide

The product may contain hydrochloric acid to adjust pH.

Differin Gel Side Effects

The company has confirmed that this product does come with the risk of certain side effects.

These side effects include dryness, redness, burning, and irritation.

However, they claim that these side effects should subside within a month and that it is unlikely that everyone will experience these side effects.

It is important to recognize that outside of the side effects that have been mentioned by the company, there are many side effects that can be caused by certain ingredients in the product.

The ingredient propylene glycol, for instance, is an incredibly toxic and dangerous ingredient that is not uncommon to find in skincare products.

It has been known to cause skin irritation, allergic reactions, neurological and cardiovascular problems, respiratory issues, and it can be toxic to the liver and kidneys.

Furthermore, propylene glycol penetrates the skin. This creates a pathway for other harmful ingredients in this product to get deeper into the skin, and potentially into the bloodstream which could cause a number of harmful effects.

How To Use Differin Gel

To get the best results out of this product, the manufacturer suggests only using it once a day.

They recommend that Differin Gel should be integrated into your morning or evening skincare routine because it can only work its best if used daily.

To use this product, you should first wash your skin thoroughly with a mild cleanser.

Then you can apply a thin layer of the acne treatment gel to your dry skin and follow up with a mild moisturizer.

You should not apply sunscreen over the gel unless you have let it dry.

It is important to use only the recommended dosage. Using more will not yield better or quicker results.

The company has stated that to avoid getting dry skin and more irritation, avoid using other products that contain salicylic acid, alpha hydroxy acid and glycol acid.

Differin Gel Reviews

On the surface, the online reviews on Differin Gel appear to be incredible.

However, many of these positive reviews are on the company website. These should be trusted with caution. There is no way of knowing if the company wrote these reviews, or if real customers did.

Furthermore, many verified purchase reviews claim that this product completely destroyed their skin.

Users claim that their skin became raw, peeled, and large amounts of painful acne started forming all over their face.

Some people claim that they broke out so badly after using this product they couldn’t even recognize their own face.

Unfortunately, many users complain that they experienced extreme pain when using this product. Not just a mild burning or stinging, but pain that was comparable to a chemical burn.

Differin Gel reviews

Where To Buy Differin Gel

You can purchase this product at major retailers such as Walmart and Target.

You can also find it on online retailers such as Amazon, and the manufacturer’s website


Does Differin Gel Really Work Or Is It A Scam?

We do not believe that Differin Gel is a scam. However, it is unclear if this product really works, or if it just works on a select type of people with a very specific type of skin and acne.

The company appears to market the product by praising the fact that they are using a new and exciting ingredient (adapalene).

They say it is as powerful as a prescription but as convenient as any over-the-counter acne treatment.

However, just because an ingredient is similar to a prescription, that doesn’t guarantee results or safety which is being confirmed by many user reviews.

Unfortunately, we feel very strongly that future customers should not use this product without extreme caution or a doctor recommendation.

The number of reviews claiming that this product caused severe pain is alarming.

Acne is a hard enough problem to deal with on its own, and there is no reason why eliminating pimples and blackheads should cause more acne or side effects that have been compared to a chemical burn.

With so many proven and safe acne fighting treatments on the market, there is no reason to waste your time, money or the health of your skin on a product that has not been proven to work.

Ultimately, it is up to you if this product is something you would like to invest in or not. 

Latest Comments:

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by LC Donovan review for Differin Gel

I experiened bouts of rashes and skin redness upon using this product. Shouldn’t the company be selling these products?

by A. Valvo review for Differin Gel

As a student chemist, I find the ingredients alarming. Many of these are dangerous!!

by Zora Klaus review for Differin Gel

It’s either my acne is too severe for this product, or this product doesn’t work at all. ?

by Benita D. review for Differin Gel

Experienced a burning effect upon application, but it disappeared after a few minutes. I’ve read reviews about its side effects. Thankfully, nothing has happened to me…..yet. Will stop using this immediately at the first sign of a side effect.